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In January 2018, plecanatide, also known by the brand name Trulance, and previously available in the United States for use in chronic idiopathic constipation, was approved by the U.S. Food and Drug Administration (FDA) for treatment of irritable bowel syndrome with constipation (IBS-C).

See this link.

https://www.healio.com/gastroenterology/irritable-bowel-syndrome/news/online/%7B0aa46942-f0d1-4b90-a703-335e5878dec4%7D/fda-approves-trulance-for-ibs-c

Updated May 2018

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IBS Impact is a grassroots group effort of people with IBS and our supporters who volunteer our own time and resources. We are not a business or a charity. If you wish to support the IBS cause, we encourage you to donate to IBS organizations or research centers in your country. Many are linked on our Research and Links pages.

News

  • April is Irritable Bowel Syndrome (IBS) Awareness Month 2025
  • Tegaserod (Zelnorm) for IBS-C Removed From U.S. Market for Business Reasons, July 2022
  • American College of Gastroenterology Publishes 2020 Clinical Guidelines for IBS Management-December 2020
  • IFFGD 2020 IBS Patients’ Illness Experience and Unmet Needs Online Survey Open For Response
  • U.S. FDA Approves Tenapanor (Ibsrela) for Adults with IBS-C, September 2019
  • U.S. FDA Approves IB-Stim, First Medical Device for IBS Pain in Adolescents with IBS, June 2019.
  • New Canadian Association of Gastroenterology Clinical Practice Guidelines for the Management of IBS– April 2019.
  • U.S. FDA Approves Return of Tegaserod (Zelnorm) to U.S. Market for Some Women with IBS-C, April 2019
  • Lupin Pharmaceuticals, Canada Announces Approval of Rifaximin (Zaxine) for IBS-D, December 2018
  • International Foundation for Functional Gastrointestinal Disorders (IFFGD) Seeking Volunteers for New Patient Panel
  • DNA Variants on Chromosome 9 May Be Associated with Increased Risk of IBS in Some Women
  • Gastrointestinal Society (Canada) Releases 2018 IBS Global Impact Report
  • U.S Food and Drug Administration (FDA) Asks Manufacturers to Limit Quantity of Loperamide (Imodium) in Packages, January 2018
  • U.S. Food and Drug Administration (FDA) Approves Plecanatide (Trulance) for Use in IBS with Constipation, January 2018
  • IBS Impact Responds to Inaccurate Media Reports on IBS and the Passing of Designer Mychael Knight, October 2017

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Please have your symptoms diagnosed by a medical practitioner or doctor. It is important to remember that you cannot self diagnose IBS and there are many serious conditions that can mimic some IBS symptoms. The leading cause of misdiagnosis is self-diagnosis.

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